Motif ID: FOX{I1,J2}.p2

Z-value: 2.117


Transcription factors associated with FOX{I1,J2}.p2:

Gene SymbolEntrez IDGene Name
FOXI1 2299 forkhead box I1
FOXJ2 55810 forkhead box J2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXI1chr5_+_169465478-0.411.2e-01Click!
FOXJ2chr12_+_8076508-0.116.9e-01Click!


Activity profile for motif FOX{I1,J2}.p2.

activity profile for motif FOX{I1,J2}.p2


Sorted Z-values histogram for motif FOX{I1,J2}.p2

Sorted Z-values for motif FOX{I1,J2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{I1,J2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_19818209 11.605 NM_018993
RIN2
Ras and Rab interactor 2
chr5_+_159368690 10.364 TTC1
tetratricopeptide repeat domain 1
chr5_+_159368721 8.889 TTC1
tetratricopeptide repeat domain 1
chr5_+_159368733 8.339 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr4_+_167013859 7.660 NM_012464
TLL1
tolloid-like 1
chr1_+_148747110 5.870 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr7_+_151284396 5.645 NM_145292
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr5_-_54317102 4.908 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr1_-_77457664 4.639 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr2_-_133145539 4.402 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr2_+_201182187 4.388 AOX1
aldehyde oxidase 1
chr4_+_86968069 4.208 ARHGAP24
Rho GTPase activating protein 24
chr2_-_40593074 4.192 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr10_+_71231693 4.009 COL13A1
collagen, type XIII, alpha 1
chr4_+_154397975 3.917 TRIM2
tripartite motif containing 2
chr10_+_71231649 3.848 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr5_+_53787187 3.738 NM_006308
HSPB3
heat shock 27kDa protein 3
chr5_-_59100194 3.617 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_-_108579270 3.535 NM_001146
ANGPT1
angiopoietin 1
chr10_-_90702490 3.440 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr19_+_57564981 3.410 NM_001145434
ZNF880
zinc finger protein 880
chr5_+_96237923 3.406 ERAP2
endoplasmic reticulum aminopeptidase 2
chr22_-_43987978 3.392 KIAA0930
KIAA0930
chr7_-_87687276 3.392 SRI
sorcin
chr8_-_93181091 3.341 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_134042500 3.270 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr22_-_41366550 3.213 NM_001165877
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr3_-_130761967 3.144 PLXND1
plexin D1
chr3_-_170970296 3.119 NM_032487
ARPM1
actin related protein M1
chr1_+_84540921 3.070 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr22_+_44828338 2.995


chr8_-_13416554 2.928 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr2_+_151922350 2.901 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr11_+_57547928 2.851 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr15_+_76345577 2.850 NM_001130183
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr3_+_46423682 2.726 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr7_+_111908143 2.724 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr2_+_36777406 2.718 VIT
vitrin
chr19_-_56946911 2.715 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr3_+_11242666 2.658 NM_001098211
HRH1
histamine receptor H1
chr10_-_14090459 2.647 FRMD4A
FERM domain containing 4A
chr9_+_130719034 2.625 LRRC8A
leucine rich repeat containing 8 family, member A
chr9_+_102380156 2.531 NM_001018116
MURC
muscle-related coiled-coil protein
chr1_+_242691295 2.501 NM_001130957
NM_173807
C1orf101

chromosome 1 open reading frame 101

chr7_-_87687302 2.460 NM_003130
SRI
sorcin
chr7_-_112513379 2.444 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr8_-_93176618 2.441 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr15_+_55298908 2.417 NM_207040
TCF12
transcription factor 12
chr3_-_115825742 2.417 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr7_-_27186400 2.406 NM_153715
HOXA10
homeobox A10
chr21_+_29439768 2.361 C21orf7
chromosome 21 open reading frame 7
chr5_+_55182963 2.356 NM_139017
IL31RA
interleukin 31 receptor A
chr10_-_31328426 2.356 NM_001143769
ZNF438
zinc finger protein 438
chr6_+_150304813 2.342 NM_025217
ULBP2
UL16 binding protein 2
chr1_+_150753601 2.323 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr9_-_8723893 2.260 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr13_-_77391525 2.234


chr7_+_113513828 2.200 FOXP2
forkhead box P2
chr1_-_242073094 2.199 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr9_-_116920232 2.183 NM_002160
TNC
tenascin C
chr5_-_36337756 2.153 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr11_+_113672378 2.145 NNMT
nicotinamide N-methyltransferase
chr12_-_14929991 2.119 NM_000900
NM_001190839
MGP

matrix Gla protein

chr21_-_42219849 2.114 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr5_+_147775652 2.107 FBXO38
F-box protein 38
chr1_-_149611768 2.104 NM_003944
SELENBP1
selenium binding protein 1
chr10_+_86174665 2.079 FAM190B
family with sequence similarity 190, member B
chr12_+_123339662 2.070 NM_181709
FAM101A
family with sequence similarity 101, member A
chr9_+_119506446 2.054 TLR4
toll-like receptor 4
chr2_-_189752575 2.052 NM_000393
COL5A2
collagen, type V, alpha 2
chr12_-_50871953 2.018 NM_001081492
NM_182507
KRT80

keratin 80

chr11_+_113672407 2.011 NNMT
nicotinamide N-methyltransferase
chr2_+_36777336 2.003 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr9_+_119506428 1.997 TLR4
toll-like receptor 4
chr9_+_112470871 1.996 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr4_-_186693574 1.978 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr9_-_16717887 1.962 BNC2
basonuclin 2
chr4_-_138673078 1.961 NM_019035
PCDH18
protocadherin 18
chr9_+_119506274 1.946 NM_138554
TLR4
toll-like receptor 4
chr1_-_177378801 1.899 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr6_+_121798443 1.898 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr2_-_215998181 1.892 FN1
fibronectin 1
chr1_+_157246305 1.890 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr7_+_136203938 1.882 NM_001006627
NM_001006630
CHRM2

cholinergic receptor, muscarinic 2

chr10_-_118022707 1.872 NM_001145453
GFRA1
GDNF family receptor alpha 1
chr4_-_153523113 1.872 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr9_+_74956601 1.870 ANXA1
annexin A1
chr12_+_118100977 1.843 NM_014365
HSPB8
heat shock 22kDa protein 8
chr4_-_186815116 1.807 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr12_+_47584159 1.804 NM_033124
CCDC65
coiled-coil domain containing 65
chr10_+_71232281 1.803 COL13A1
collagen, type XIII, alpha 1
chr14_+_78815406 1.799 NM_001105250
NM_138970
NRXN3

neurexin 3

chr4_+_71806538 1.786 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr5_-_59100091 1.756 PDE4D
phosphodiesterase 4D, cAMP-specific
chrX_-_23955223 1.750 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr15_+_65205107 1.743 NM_001145102
SMAD3
SMAD family member 3
chr1_+_66570683 1.738 PDE4B
phosphodiesterase 4B, cAMP-specific
chr8_+_75066117 1.727 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr3_-_21767819 1.724 NM_024697
ZNF385D
zinc finger protein 385D
chr3_+_62280435 1.724 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr9_+_129900637 1.716 NM_052901
NM_001006643
SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

chr4_+_72321113 1.707 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr1_+_66570363 1.703 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr9_+_5500544 1.696 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr13_+_22653059 1.686 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr8_-_93177057 1.682 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr6_+_134800533 1.659 LOC154092
hypothetical LOC154092
chrX_-_43717864 1.654 NM_000266
NDP
Norrie disease (pseudoglioma)
chr4_-_186814852 1.643 SORBS2
sorbin and SH3 domain containing 2
chr9_+_129900590 1.636 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr17_+_55098280 1.627 CLTC
clathrin, heavy chain (Hc)
chr12_-_9913199 1.625 CLEC2B
C-type lectin domain family 2, member B
chr7_-_92615593 1.612 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chrX_+_100361588 1.612 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr7_+_113513600 1.603 FOXP2
forkhead box P2
chr3_+_45042754 1.598 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr3_-_102194938 1.591 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr1_+_84382529 1.590 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_-_183095308 1.590 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr2_-_179380301 1.577 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr6_+_116939500 1.575 NM_153711
FAM26E
family with sequence similarity 26, member E
chr11_-_72111027 1.571 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr1_+_77105746 1.568 NM_030965
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr1_-_161439487 1.555 NM_003617
RGS5
regulator of G-protein signaling 5
chr5_+_15553288 1.538 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr8_-_52884456 1.532 NM_144651
PXDNL
peroxidasin homolog (Drosophila)-like
chr3_+_116824840 1.530 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr6_+_153060722 1.529 NM_025107
MYCT1
myc target 1
chr12_-_90100679 1.514 DCN
decorin
chr13_+_20081940 1.510


chr9_+_77695334 1.506 NM_001190482
NM_006200
PCSK5

proprotein convertase subtilisin/kexin type 5

chr9_-_25668855 1.497 NM_001004125
TUSC1
tumor suppressor candidate 1
chr8_-_24869945 1.490 NM_006158
NEFL
neurofilament, light polypeptide
chr10_-_118021532 1.490 NM_145793
GFRA1
GDNF family receptor alpha 1
chr2_+_33514896 1.483 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr3_-_188936941 1.475 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr1_+_82038669 1.459 NM_012302
LPHN2
latrophilin 2
chr1_+_77105709 1.451 ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr7_+_119700924 1.451 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr1_-_21373816 1.447 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr2_-_225519974 1.424 DOCK10
dedicator of cytokinesis 10
chr3_-_55489973 1.417 WNT5A
wingless-type MMTV integration site family, member 5A
chr13_+_96592051 1.407 MBNL2
muscleblind-like 2 (Drosophila)
chr8_-_93176819 1.405 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_+_26322168 1.403 RNF135
ring finger protein 135
chr3_-_11598829 1.398 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr11_+_7997366 1.396 TUB
tubby homolog (mouse)
chr7_+_150442652 1.394 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr2_+_102320148 1.392 NM_003856
IL1RL1
interleukin 1 receptor-like 1
chr12_+_27066749 1.392 NM_004264
MED21
mediator complex subunit 21
chr1_-_89437098 1.384 NM_052941
GBP4
guanylate binding protein 4
chr4_-_70861301 1.382 NM_001891
CSN2
casein beta
chr10_+_94584449 1.379 NM_001013848
EXOC6
exocyst complex component 6
chr12_+_29193399 1.375 FAR2
fatty acyl CoA reductase 2
chr6_-_138935359 1.369 NM_020464
NHSL1
NHS-like 1
chr17_+_26322081 1.357 NM_001184992
NM_032322
NM_197939
RNF135


ring finger protein 135


chr9_+_74956494 1.355 NM_000700
ANXA1
annexin A1
chr3_-_145049853 1.355 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr12_-_90100733 1.353 NM_001920
DCN
decorin
chr12_+_27066768 1.347 MED21
mediator complex subunit 21
chr3_-_170346760 1.343 NM_001105077
NM_001163999
NM_005241
MECOM


MDS1 and EVI1 complex locus


chr1_+_156229686 1.331 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr11_-_8695974 1.331 ST5
suppression of tumorigenicity 5
chr17_-_44006808 1.331 NM_002146
HOXB3
homeobox B3
chr3_+_35696119 1.321 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr11_+_101488380 1.316 NM_001195045
YAP1
Yes-associated protein 1
chr1_-_110735158 1.316 NM_004696
SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr7_-_143213296 1.315 FAM115A
family with sequence similarity 115, member A
chr8_-_93144039 1.302


chr20_+_42644633 1.301 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr13_-_32757835 1.295 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr5_+_54491702 1.291 NM_001008397
GPX8
glutathione peroxidase 8 (putative)
chr13_+_75092570 1.284 NM_005358
LMO7
LIM domain 7
chr5_+_152850276 1.277 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr16_+_28993770 1.273 RRN3P2
RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2
chr4_+_15080586 1.267 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr8_+_70567581 1.265 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr1_+_84382562 1.263 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_210152399 1.262 MAP2
microtubule-associated protein 2
chr10_-_118022965 1.253 NM_005264
GFRA1
GDNF family receptor alpha 1
chr13_-_32678142 1.240 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr13_-_95092283 1.239 DZIP1
DAZ interacting protein 1
chr12_-_2814410 1.235 NM_031474
NRIP2
nuclear receptor interacting protein 2
chr3_-_113841200 1.224 CCDC80
coiled-coil domain containing 80
chr7_+_17349425 1.223 AHR
aryl hydrocarbon receptor
chr20_+_10147455 1.217 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chrX_+_135106578 1.210 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr21_+_39117064 1.208 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr9_+_674193 1.198


chr1_-_171286634 1.198 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr11_-_121492010 1.195 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr6_-_56615544 1.195 NM_001723
NM_015548
DST

dystonin

chr6_-_112682401 1.194 LAMA4
laminin, alpha 4
chr15_+_37330176 1.179 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr3_-_191321367 1.175 LEPREL1
leprecan-like 1
chr7_-_13997574 1.175 NM_001163148
ETV1
ets variant 1
chr9_+_12764988 1.173 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr8_-_93144366 1.172 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_69895651 1.171 NM_006722
MITF
microphthalmia-associated transcription factor
chr12_+_46799279 1.168 NM_000289
PFKM
phosphofructokinase, muscle

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.94 2.92e-03 GO:0022603 regulation of anatomical structure morphogenesis
2.51 3.31e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.49 4.00e-03 GO:0022604 regulation of cell morphogenesis
1.55 1.18e-02 GO:2000026 regulation of multicellular organismal development
1.47 3.00e-02 GO:0050793 regulation of developmental process
1.27 4.14e-02 GO:0048519 negative regulation of biological process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.20 7.80e-04 GO:0071944 cell periphery
1.20 1.34e-03 GO:0005886 plasma membrane
1.85 1.82e-03 GO:0005578 proteinaceous extracellular matrix
1.90 1.09e-02 GO:0016323 basolateral plasma membrane
1.61 4.94e-02 GO:0045202 synapse

Nothing significant found in function category.